United States Patent 4,760,071
Rasmusson, et. al. Jul. 26, 1988

17.beta.-N-monosubstituted carbamoyl-4-aza-5.alpha.-androst-1-en-3-ones which are active as testosterone 5.alpha.-reductase inhibitors

Inventors: Rasmusson; Gary H. (Watchung, NJ); Reynolds; Glenn F. (Westfield, NJ).
Assignee: Merck & Co., Inc. (Rahway, NJ).
Appl. No.: 800,623
Filed: Nov. 21, 1985


This invention is for the compound 17.beta.-(N-t-butylcarbamoyl)-4-aza-5.alpha.-androst-1-en-3-one, pharmaceutical compositions containing the compound, methods of inhibiting testosterone 5.alpha.-reductase with the compound and methods of treating hyperandrogenic conditions with the compound, particularly benign prostatic hypertrophy.

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