| ( 1 of 3 ) |
| United States Patent | 5,472,687 |
| Proctor | Dec. 5, 1995 |
| Inventors: | Proctor; Peter H. (Twelve Oaks Medical Towers 4126 SW. Freeway, Suite 1616, Houston, TX 77027). |
| Appl. No.: | 193,228 |
| Filed: | Feb. 7, 1994 |
Related U.S. Application Data
| Continuation-in-part of Ser No. 21,970, Feb. 24, 1993, Pat. No. 5,352,442, which is a continuation-in-part of Ser. No. 149,720, Jan. 29, 1988, abandoned, which is a continuation-in-part of Ser. No. 8,186, Jan. 28, 1987, abandoned, which is a continuation-in-part of Ser. No. 858,050, Apr. 30, 1986, abandoned, which is a continuation-in-part of Ser. No. 757,131, Jul. 18, 1985, abandoned. |
Primary Examiner: Nazario-Gonzales; Porfirio
Attorney, Agent or Firm: Sroufe, Payne & Lundeen
Topical pyridine N-oxides, including 3-carboxypyridine N-oxide, niacinamide N-oxide, and .alpha.-(4-pyridyl-1-oxide)-N-t-butylnitrone, are disclosed. The topical compositions have utility in a topical pharmaceutical formulation for the cosmetic treatment of hair loss and the cosmetic stimulation of hair growth.
10 Claims, No Drawings
Hair loss
keywords: alopecia antioxidant redox signaling free radical nxy-059 dermatitis regrowth pbn dmpo tempo nitric oxide no peroxinitrite superoxide peroxide nitrate loss products nitrone nitroxide parkinson, reperfusion altzheimer endothelium ros.