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|United States Patent||5,472,687|
|Proctor||Dec. 5, 1995|
|Inventors:||Proctor; Peter H. (Twelve Oaks Medical Towers 4126 SW. Freeway, Suite 1616, Houston, TX 77027).|
|Filed:||Feb. 7, 1994|
Related U.S. Application Data
|Continuation-in-part of Ser No. 21,970, Feb. 24, 1993, Pat. No. 5,352,442, which is a continuation-in-part of Ser. No. 149,720, Jan. 29, 1988, abandoned, which is a continuation-in-part of Ser. No. 8,186, Jan. 28, 1987, abandoned, which is a continuation-in-part of Ser. No. 858,050, Apr. 30, 1986, abandoned, which is a continuation-in-part of Ser. No. 757,131, Jul. 18, 1985, abandoned.|
Primary Examiner: Nazario-Gonzales; Porfirio
Attorney, Agent or Firm: Sroufe, Payne & Lundeen
Topical pyridine N-oxides, including 3-carboxypyridine N-oxide, niacinamide N-oxide, and .alpha.-(4-pyridyl-1-oxide)-N-t-butylnitrone, are disclosed. The topical compositions have utility in a topical pharmaceutical formulation for the cosmetic treatment of hair loss and the cosmetic stimulation of hair growth.
10 Claims, No Drawings
keywords: alopecia antioxidant redox signaling free radical nxy-059 dermatitis regrowth pbn dmpo tempo nitric oxide no peroxinitrite superoxide peroxide nitrate loss products nitrone nitroxide parkinson, reperfusion altzheimer endothelium ros.